… bind peptides stably but non-specifically! The solution of the MHC class II crystal structure, …
The CLIP region was shown to binds to the groove of MHC II molecules in the endoplasmic …

… The results showed that the optimal number of immunoglobulin binding domains to
induce the largest B-cell response was 5 (95). This observation suggests that B-cell …

… the solution-phase HDX-MS data suggest a binding affinity of … observed between superantigens
and the TCR Vβ domain. … region with cognate pMHC could be due to minor structural …

… with solutions of various soluble TCR s at 5 μg/ ml until binding to … in the ɑ helical region of
the MHC class I ɑ1 domain (14). … The Vß-specific superantigen Staphylococcal enterotoxin B: …

… as bacterial superantigens (SAgs), which cross-link major … -bridge the major histocompatibility
complex class II (MHC II) with … SEN structure shows the classical two-domain superantigen …

… the addition of 5 mL of 10 mM solution of EDTA in phosphate … class II molecules in a region
outside of the peptide binding … Superantigens interact with MHC class II molecules outside …

… -link major histocompatibility complex (MHC) class II molecules … class II binding site can be
found in the β-grasp domain of some SAgs, and interacts with the β-chain of the MHC class II …

… , important residues that are vital for the T-cell receptor (TcR) and major histocompatibility
complex class II (MHC-II… antigen binding domain, whether our predicted superantigen can also …

… TCR) and major histocompatibility complex class II, triggering … Due to high stability and
toxicity, superantigens are potential … bind to MHC class II, they either use the N-terminal domain, …

… from different functional domains of the FBP1 sequence. … superantigen capacities. We identified
earlier fibronectin-… synthesis of MHC (major histocompatibility complex) class II tetramers. …